Monday, May 20, 2013

Why do People Get Lupus Nephritis

Definition
Lupus Nephritis is a kind of kidney damage which is caused by Systematic Lupus Nephritis. Systematic Lupus Nephritis (SLE) is also a kind of immune disease. In addition, from cytology, Systematic Lupus Nephritis is a kind of renal epithelial cell disease of capillary vessels. At present, doctors judge the disease by this.
Pathological factors
After patients are infected by lupus, excessive immune response will come into being and exist, which leads to the pathological self-antibody. In this case, a large amount of immune complex comes into being. C3、lgG、lgM and so on will deposit on renal capillary epithelial cells. At this time, the immune mediator in renal capillary epithelial cells will come into being, so the normal function of renal capillary epithelial cells will be damaged as well. There are negative charges barrier in the epithelial cells. After the function is damaged, protein will pass and flow into urine, thus causing proteinuria. From the urine report, we can find out that there are pluses. Renal function will be damaged accordingly.
Treatment principle
To treat Systematic Lupus Nephritis (SLE), we should follow the following procedures.
Firstly, extending blood vessels, the purpose of which is to improve the blood circulation in the kidney, relieve the insufficiency of blood and oxygen in the blood, thus creating a favorable environment for the repair of epithelial cells and mesangial cells.
Secondly, anti-inflammation, the purpose of which is to reduce the infiltration of inflammatory cells and relieve the further damage of renal epithelial cells.
Thirdly, anticoagulation, the purpose of which is to relieve of pressure which forms thrombus and lay a foundation for the repair of epithelial cells.
Fourthly, degradation, which is used to clear the immune complex and matrix and helps them discharge out of the body.
Medicines
As for the medicine, patients with Systematic Lupus Nephritis (SLE) are recommended to take combination of western medicine and Chinese medicine, which can achieve better effect than only either of them for either western medicine or Chinese medicine has restriction. In our hospital, we have created six-step immune therapy on the basis of this theory, which can repair the damaged intrinsic cells as well as increase the immune ability.

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