Wednesday, May 15, 2013

GFR 14, Urine 200ml under Dialysis

One of my patients is suffering from diabetic nephropathy. 16 years ago, she was diagnosed with diabetes. Now she is under dialysis. And she takes dialysis three times a week. Her creatinine is 228 umol/L. Through ECT, the GFR is 14, which indicates that she has already in uremia stage. Her urine is 200ml per day. My patient Mrs Read told me that now her biggest dream is to stop dialysis one day. She asked me whether she can realize it.
Firstly, I told her that as long as she has urine, it indicates that there is blood flow in kidney. In this case, medicines can reach the kidney, thus playing therapeutic effect. Secondly, as long as the GFR is more than 5, there will be hope. As long as the GFR rises to 10 to 15, we can take effective measures to reduce the times of dialysis. And when the GFR is more than 15, renal failure patients can get rid of dialysis.
So from the above, we can get a conclusion that according my patient Mrs Read’s condition, she can realize her dream. To achieve it, what should we do? In this passage, we will mainly introduce the immunotherapy, which can be generally divided into 6 steps and contains mainly Chinese Medicine and stem cell.
Firstly, after patients are discharged in our hospital, we will arrange a systematic and scientific physical examination for them, the purpose of which is to know the type of pathological damage and where the immune complex deposits on earth. All this can supply evidence for the treatment plan of doctor in clinic.
Secondly, medicines are used to inhibit the immune response. In Chinese Medicine, there are active and nutritious herbs which can increase the immune ability as well as improve the blood circulation, repair the damaged intrinsic cell, thus rebuilding renal structure and reviving renal function. Generally, patients receive Chinese Medicine once a day, and each lasts for 45 minutes.
Thirdly, stem cell is applied in clinic, which is especially proper for the repair of diabetes. Stem cells can repair beta cells. Through repairing islet, new islet beta cells can be born and pancrease can have function of secreting insulin again. Factors which come into being by stem cell can stimulate the regeneration of islet beta cells. Stem cells can also repair other cells which insulin secrets. In the human body, islet beta cells can secret insulin, and besides, in other tissues and organs, there are also other cells which can play the same roles. Stem cells can repair the damaged ones, and increase the secretion amount, thus making blood sugar decrease. In addition, stem cells can also differentiate into cells which the kidney needs and increase the immune ability as well.
After these, diabetic nephropathy can not only be treated and will not recur easily. Day by day, patients such as Mrs Read can get rid of dialysis as well.

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