Patients who are in stage 4 of Lupus Nephritis may fall in desperate and think that they some day may lost their life. Please do not worry, and we will explain it for you in detail and recommend a good treatment method for you.
Systemic Lupus Erythematosus (SLE) is an autoimmune disease, which occurs every now and then, and becomes worse and worse with the recurrence. In stage 4 of chronic kidney disease, patients with lupus nephritis usually have symptoms such as red blood cells, white blood cells and protein in urine, high blood pressure, rash, especially butterfly rash on the face, anemia and so on, all of which make people with Lupus Nephritis suffer and lose confidence for many of them have already begun to take dialysis due to long time high serum creatinine. After realizing dialysis can not repair the damage inside of the kidney, has some adverse side effects and some complications, patients begin to doubt. In this passage, we would like to introduce a better therapy which is called stem cell therapy.
As we mentioned above, Lupus Nephritis is an autoimmune disease. Autoantibody can protect us when pathological factors invade such as bacteria and virus, which can not react to the tissues and elements of our body. It plays functions depending on the tolerance of the whole immune. One the tolerance is damaged, our organic body will consider our own tissues abnormal substances, which leads to autoimmune reaction, causing autoantibody. In normal condition, in the blood, there is a small amount of autoantibody, which will not lead to disease. Once the amount is excess, it will damage the body and leads to kinds of autoimmune disease.
Stem cell’s most important function is differentiation and to increase the immune ability of patients. Stem cell can regenerate into many capillary endothelial cells and repair the damaged renal membrane, repair the filtration membrane, improve the filtration function, thus improving the renal glomerular filtration.
In addition, stem cell can also generate into munologic balance cells such as Ts cells, Th cells, etc. Stem cell can also balance the immunoreaction, diminish a variety of factors which can cause renal glomerular disease, avoid the continuous damage to renal tubules, thus reviving renal function consequently.