Mesangial Proliferative Glomerulonephritis accounts for 50% among those who have renal biopsy, and takes up 30% of those who are diagnosed with primary nephrotic syndrome. Half of patients have had infection before, and males are more than females. About 70 percent of them have hematuria, most of which is microscopic hematuria. With Mesangial Proliferative Glomerulonephritis developing, more and more patients will develop into renal failure and have high blood pressure. So effective treatment is urgent and critical.
However, before we talk about the treatment, it is necessary to explain why it comes into being. It is believed that Mesangial Proliferative Glomerulonephritis is a kind of immune mediator disease. When the clearance function of mesangial tissues decreases or is inhibited, mononuclear phagocyte’s function will be damaged. In this case, immune complex can not be cleared away and they deposit on the mesangial area, leading to lesion in mesangial area.
So from the above, we can get a conclusion that to treat Mesangial Proliferative Glomerulonephritis, we should focus on the clearance of immune complex. On the basis of this, experts summed up a systematic immunotherapy which can be divided into 6 main steps: systematic immune diagnosis, immune clearance, immune inhibition, immune adjustment, immune protection.
After patients with Mesangial Proliferative Glomerulonephritis comes to our hospital, we will arrange a more systematic diagnosis for him or her, which he can not get in other hospitals, the purpose of which is to figure out where exactly the immune complex is and the amount of immune complex. Only when we figure it out, can we decide what medicine doctors use and the amount we will use. If the amount is too much, it will lead to more side effects and if the amount is not enough, the effect can not achieve.
Immune clearance means that we use blood purification technology to clear away the immune complex in the blood, which can reduce the damage caused by immune response. In the immune adjustment and immune protection steps, medicine which can promote blood circulation, dissolve the stasis, and increase the immune ability are used such as Chinese Medicine and stem cell transplant. In addition, some western medicine is also widely used in it so as to assist Chinese Medicine and stem cell.
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