Minimal Change Kidney Disease Symptoms

What are the symptoms of minimal change kidney disease? Many kidney disease patients with minimal change want to know about the symptoms of minimal change kidney disease.
Children aged 2 to 6 are usually found out to suffer from minimal change kidney disease while adults aged 30 to 40 are often seem to have got minimal change kidney disease. What’s more, advanced people who are more than 60 years old also have high morbidity. Among children sufferers, the morbidity of boys is twice as high as that of girls. As for adult, the ratio of man and woman is equally one to one. About one third of patients have infection in the upper respiratory tract or other infection. The most typical symptoms are obvious Nephrotic Syndrome, which takes up 90% of children Nephrotic Syndrome and 20% of adult Nephrotic Syndrome. Blood pressure is normal.
20% of patients with minimal change kidney disease have various degree of microscopic hematuria. With patients aging, the morbidity of microscopic hematuria is also increasing. Especially in those aged more than 60, due to renal interstitial fibrosis and diabetic microangiopathy, the morbidity of microscopic hematuria is high. However, gross hematuria is rarely seem. Because blood volume is low and renal perfusion decreases, about one third of patients with minimal change kidney disease have declined GFR. Through the examination of urinary sediment, cells or cast can not be found. Among those who are serious, the protein in urine is more than 40g with 24 hours.
Protein in urine is the typical highly selective one among children, which mainly includes albumin, and a slight amount of HMWP such as IgG, α2- macroglobulin, C3, etc.
Patients with minimal change kidney disease should be aware of Hodgkin's disease. In addition, nephrotic syndrome caused by allergy of steroid expectorant is also similar to minimal change kidney disease, accompanied by interstitial nephritis and renal decline.
In rare cases, acute renal failure can occur when there is no obvious low blood volume. Because hypoproteinemia leads to the decrease of colloid osmotic pressure, only 7% to 38% of patients with low blood volume have prerenal axotemia. If there is no typical hypovolemia, urine concentrating power will decline and sodium will discharge out together from urine.