Diabetic Nephropathy 17 Years, on Dialysis

                Diabetic Nephropathy is a secondary kidney disorder which is caused by long time diabetes. Diabetes is a disease which can lead to damage to all capillaries in the system due to long time high blood glucose. Kidney is an organ which will be damaged as well.

Long time Diabetes without enough insulin and with high blood glucose and immune dysfunction leads to a series of pathological changes of glomerular intrinsic cells, which causes broadening of glomerular basilar membrane, narrowing of lumen. It results in the shrinking of   blood vessel, which causes ischemia and anoxia of kidney, damage of capillaries surrounding glomerular and tubules and further inflammation infiltration. It starts the process of renal fibrosis. Kidney fibrosis refers to healthy kidney intrinsic cells are replaced by large quantity of extracellular matrix which can develop into glomerulosclerosis and tubular necrosis.

Generally, after 10 to 20 years, many diabetics will develop into Diabetic Nephropathy and serum creatinine will rise. When serum creatinine rises to 450umol/L, patients with Diabetic Nephropathy will take dialysis. What can we do in this case?

As we mentioned in the above, Diabetic Nephropathy is caused by diabetes, so we should treat kidney disease as well as diabetes. Stem cell is the best therapy to treat diabetes till now.

The mechanism goes as follows: pancreas islet β cells are damaged, which leads to insufficient secretion of insulin. In this case, the blood sugar will increase. If this can not be treated or controlled well, it will lead to systematic disorder and a series of complications will occur as well. Stem cells can repair the damaged pancreas islet β cells, thus recovering the function of insulin. In this case, the secretion of insulin can turn normal and diabetes can recover consequently.

As for kidney disorder caused by diabetes, we should use Chinese Medicine when creatinine is not too high and dialysis doesn’t last for a long time. Chinese Medicine can improve the blood flow in the kidney, increase the amount of urine. It can also repair the damaged intrinsic cells in the kidney, thus reviving renal function.