Diabetic Nephropathy is a relatively serious complication of diabetes. We should try to control diabetes so as to prevent the happening of Diabetic Nephropathy. What are the symptoms of Diabetic Nephropathy?
1. edema
Generally, most patients with Diabetic Nephropathy do not have edema. Some of them have slight edema before the protein in plasma declines. When the protein in 24 hours is more than 3g, edema will come into being. Those who have obvious edema have rapid development of diabetic nephropathy.
2. anemia
Anemia can be seen in Diabetic Nephropathy patients who have obvious azotemia. They can also have slight anemia, which can not achieve effects with chalybeate. When the generation of red cells are damaged or blocked, anemia will come into being, which can also be related to long time limitation of protein and anemia.
3. high blood pressure
High blood pressure is common in patients with Diabetic Nephropathy, which can accelerate the development of Diabetic Nephropathy. So controlling high blood pressure is essential.
4. proteinuria
In the beginning, due to the change of increased filtration pressure in renal glomerulus and the change of charge in the renal glomerular filtration membrane, there is only a small amount of protein in urine, which is called microalbumin. With the filtration pore of renal glomerulus increasing, some big molecules can also filtrate out, which leads to proteinuria. If not controlled well, the proteinuria will develop into continuous and serious proteinuria. If the protein which leaks out into urine every day is more than 3 g, we can not get a good prognosis. At last, nephrotic syndrome will come into being.
So the earlier we find out Diabetic Nephropathy, the better effect of treatment we will get.
Tuesday, June 4, 2013
Risk Factors of Diabetic Nephropathy
With more and more people suffering from Diabetes, Diabetic Nephropathy followed closely. Kidney disease is a serious complication of Diabetes, the lethallty of which is high. What’s more, Diabetic Nephropathy can not be found out in the early stage. So when people are diagnosed with Diabetic Nephropathy, they may have become into the end stage and Diabetic Nephropathy have to receive dialysis and chemical therapy to maintain life. So patients with Diabetes must prevent the disease from developing into Diabetic Nephropathy. What are the risk factors of Diabetic Nephropathy?
The first risk factor for patients with Diabetic Nephropathy is blood pressure, which is a symptom in the end stage and appears in those who have been suffering from protein in urine for a long time. At the early stage, blood pressure will not increase until patients take exercise. When patients with Diabetic Nephropathy have continuous protein in urine, blood pressure will increase continuously. The existence of high blood pressure accelerates the deterioration of renal function for patients with Diabetic Nephropathy.
The second risk factor for patients with Diabetic Nephropathy is edema and Nephroic Syndrome. About half of patients with Diabetic Nephropathy have edema, which may be due to the lost of large amount of protein in urine. However, the older the patients are, there will be more reasons which can cause edema. What’s more, about 20% of patients with Diabetic Nephropathy have Nephroic Syndrome.
The third risk factor for patients with Diabetic Nephropathy is renal failure. At the early stage, they should control the sugar in blood. Glomerular filtration rate increases in this stage. Blood urea nitrogen in blood and serum creatinine are normal. After continuous protein in urine appears, the density of blood urea nitrogen in blood and serum creatinine will increase. And renal insufficiency will come into being as well. Several years later, it can develop into end-stage renal failure. In addition, Diabetic Nephropathy is usually accompanied with kinds of complications. What’s more, acute renal failure may also come into being.
So patients with Diabetic Nephropathy are suggested to receive timely treatment as soon as possible.
The first risk factor for patients with Diabetic Nephropathy is blood pressure, which is a symptom in the end stage and appears in those who have been suffering from protein in urine for a long time. At the early stage, blood pressure will not increase until patients take exercise. When patients with Diabetic Nephropathy have continuous protein in urine, blood pressure will increase continuously. The existence of high blood pressure accelerates the deterioration of renal function for patients with Diabetic Nephropathy.
The second risk factor for patients with Diabetic Nephropathy is edema and Nephroic Syndrome. About half of patients with Diabetic Nephropathy have edema, which may be due to the lost of large amount of protein in urine. However, the older the patients are, there will be more reasons which can cause edema. What’s more, about 20% of patients with Diabetic Nephropathy have Nephroic Syndrome.
The third risk factor for patients with Diabetic Nephropathy is renal failure. At the early stage, they should control the sugar in blood. Glomerular filtration rate increases in this stage. Blood urea nitrogen in blood and serum creatinine are normal. After continuous protein in urine appears, the density of blood urea nitrogen in blood and serum creatinine will increase. And renal insufficiency will come into being as well. Several years later, it can develop into end-stage renal failure. In addition, Diabetic Nephropathy is usually accompanied with kinds of complications. What’s more, acute renal failure may also come into being.
So patients with Diabetic Nephropathy are suggested to receive timely treatment as soon as possible.
Five Stages of Diabetic Nephropathy
Five Stages of Diabetic Nephropathy can be divided into five stages according to the change of renal function, structure and clinical manifestation. Now this classification has been accepted by many clinical doctors. The detailed manifestations go as follows:
The first stage is renal glomerular high filtration stage. GFR(glomerular filtration rate)increase, and the size of kidney becomes bigger are the main feature of this stage. Even patients who have been diagnosed with this disease just now can have this kind of change. At the same time, the renal blood volume, the perfusion of capillary blood vessels and the inner pressure all increase. The damage in this stage is reversible. In other words, it can turn normal after injection of insulin. But usually complete recover is difficult to achieve.
In the second stage, protein which is discharged into urine is normal. However, the structure of glomeruli in this stage is changed already. The membrane of renal glomerular capillary blood vessels increases. The matrix in mesangium increases as well. GFR(glomerular filtration rate)level is normal and corresponds with blood sugar. GFR(glomerular filtration rate)is more than 150mL/min. The glycosylated hemoglobin is often more than 9.5%. Patients with Diabetic Nephropathy often have normal blood pressure in the first and second stage.
In the third stage, UAE is continuously higher than 20~200ug/min. High filtration may be the main reason for continuous albumin. Of course, it is also due to the long time not control of metabolism. In this stage, blood pressure is a little high. Declining blood pressure can reduce the discharge of albumin to some degree.
In the fourth stage, the characteristic of Diabetic Nephropathy is large amount of protienuria. UAE is more than 200pg/min, which is nonselective proteinuria. In this stage, blood pressure increases. GBM becomes thicker obviously.The matrix of mesangium becomes wider. Deserted glomeruli increases, which takes up about 36%.
With a lot of protein lost in urine, patients can have hypoproteinemia and edema, which form the typical characteristic of Diabetic Nephropathy. Edema is relatively serious and has poor reaction to diuretic. Besides due to low protein in plasma, patients also have retention of sodium. That’s because insulin changed the sodium in tissues. Long time high insulin use can lead to the metabolic change of sodium, especially when patients keep high sodium diet.
In the fifth stage, patients with Diabetic Nephropathy may suffer from continuous large amount of proteinuria and develop into clinical Diabetic Nephropathy stage. The basilar membrane of glomeruli becomes thicker. More glomeruli become necrotic. Renal function declines progressively, which leads to renal failure. Blood pressure also increases. Edema and hypoproteinemia can also be diagnosed. Patients with Diabetic Nephropathy mostly have gastrointestinal reaction caused by azotemia such as declined appetite, vomiting, nausea, and even serious high blood pressure, edema and so on.
The first stage is renal glomerular high filtration stage. GFR(glomerular filtration rate)increase, and the size of kidney becomes bigger are the main feature of this stage. Even patients who have been diagnosed with this disease just now can have this kind of change. At the same time, the renal blood volume, the perfusion of capillary blood vessels and the inner pressure all increase. The damage in this stage is reversible. In other words, it can turn normal after injection of insulin. But usually complete recover is difficult to achieve.
In the second stage, protein which is discharged into urine is normal. However, the structure of glomeruli in this stage is changed already. The membrane of renal glomerular capillary blood vessels increases. The matrix in mesangium increases as well. GFR(glomerular filtration rate)level is normal and corresponds with blood sugar. GFR(glomerular filtration rate)is more than 150mL/min. The glycosylated hemoglobin is often more than 9.5%. Patients with Diabetic Nephropathy often have normal blood pressure in the first and second stage.
In the third stage, UAE is continuously higher than 20~200ug/min. High filtration may be the main reason for continuous albumin. Of course, it is also due to the long time not control of metabolism. In this stage, blood pressure is a little high. Declining blood pressure can reduce the discharge of albumin to some degree.
In the fourth stage, the characteristic of Diabetic Nephropathy is large amount of protienuria. UAE is more than 200pg/min, which is nonselective proteinuria. In this stage, blood pressure increases. GBM becomes thicker obviously.The matrix of mesangium becomes wider. Deserted glomeruli increases, which takes up about 36%.
With a lot of protein lost in urine, patients can have hypoproteinemia and edema, which form the typical characteristic of Diabetic Nephropathy. Edema is relatively serious and has poor reaction to diuretic. Besides due to low protein in plasma, patients also have retention of sodium. That’s because insulin changed the sodium in tissues. Long time high insulin use can lead to the metabolic change of sodium, especially when patients keep high sodium diet.
In the fifth stage, patients with Diabetic Nephropathy may suffer from continuous large amount of proteinuria and develop into clinical Diabetic Nephropathy stage. The basilar membrane of glomeruli becomes thicker. More glomeruli become necrotic. Renal function declines progressively, which leads to renal failure. Blood pressure also increases. Edema and hypoproteinemia can also be diagnosed. Patients with Diabetic Nephropathy mostly have gastrointestinal reaction caused by azotemia such as declined appetite, vomiting, nausea, and even serious high blood pressure, edema and so on.
How to Prevent Diabetic Nephropathy
How to prevent diabetic nephropathy? The most essential method is to control blood sugar. The ideal level of blood sugar is FBG<6mmol/l, P2hBG<7.8mmol/l,HbAlc<7%. If they are not more than 7mmol/l,10mmol/l,8%, it means it is normal. However, if they are more than 7mmol/l,10mmol/l,8%, it is not ideal.
Generally, the prevention of diabetic nephropathy can be divided into 3 levels.
In the first level, we should prevent normal albuminuria from microalbuminuria.
In the second level, patients with diabetic nephropathy will develop into stage 3 to stage 4. In these two stages, we should control blood sugar and delay microalbuminuria to obvious proteinuria.
In the third level, patients with diabetic nephropathy will develop into stage 4 to stage5. In these two stages, although we control the blood sugar well, protein in urine will increase and will not decrease. Diabetic nephropathy is developing.
So from the above, we can get a conclusion that the earlier we start treatment, the better therapeutic effects we will get.
In addition, diabetic nephropathy is a secondary kidney disease which is caused by long time diabetes. So to prevent diabetes developing into diabetic nephropathy, we should control the diet and take part in more exercise so as to loose weight and to increase the sensibility of insulin. In addition, it can also decrease the hyperinsulinemia and improve the glucose tolerance. Besides, we should also take in medicine which can decrease blood sugar, decrease blood pressure and adjust blood fat at the same time.
Once diagnosed with diabetic nephropathy, please do not worry. We have immunotherapy, which contains both Chinese medicine and western medicine such as stem cell therapy, the combination of which can give you a satisfactory effect. So my dear friend, please be confident. Many doctors accompany you.
Generally, the prevention of diabetic nephropathy can be divided into 3 levels.
In the first level, we should prevent normal albuminuria from microalbuminuria.
In the second level, patients with diabetic nephropathy will develop into stage 3 to stage 4. In these two stages, we should control blood sugar and delay microalbuminuria to obvious proteinuria.
In the third level, patients with diabetic nephropathy will develop into stage 4 to stage5. In these two stages, although we control the blood sugar well, protein in urine will increase and will not decrease. Diabetic nephropathy is developing.
So from the above, we can get a conclusion that the earlier we start treatment, the better therapeutic effects we will get.
In addition, diabetic nephropathy is a secondary kidney disease which is caused by long time diabetes. So to prevent diabetes developing into diabetic nephropathy, we should control the diet and take part in more exercise so as to loose weight and to increase the sensibility of insulin. In addition, it can also decrease the hyperinsulinemia and improve the glucose tolerance. Besides, we should also take in medicine which can decrease blood sugar, decrease blood pressure and adjust blood fat at the same time.
Once diagnosed with diabetic nephropathy, please do not worry. We have immunotherapy, which contains both Chinese medicine and western medicine such as stem cell therapy, the combination of which can give you a satisfactory effect. So my dear friend, please be confident. Many doctors accompany you.
Sunday, June 2, 2013
Can Diabetes Patients Have Bananas
Can diabetes patients have bananas? Patients with diabetes are suggested to control body weight, to take more exercise and limit food especially those rich in sugar or glucose. Banana is a kind of very popular fruit all around the world which is rich in vitamin and so on. It tastes sweet and soft, which advanced people are fond of so much. Bananas also contain some trace element, which is valued by many people.
However, can diabetes patients have bananas? The answer is that at the beginning of diabetes, people should limit the amount of bananas for it contains much sugar and the blood sugar level of diabetes patients is high. If we take in many bananas, it will increase blood sugar or glucose and worsen diabetes.
In addition, bananas also contain much potassium. If patients with diabetes develop into diabetic nephropathy, there may be high potassium in the blood especially in the advanced stage of diabetic nephropathy. In this case, if we take in more bananas, we will increase the disorder of electrolyte in the body.
So from the above, we can get a conclusion that we should pay attention to the intake of bananas. For more information, please surf on our website or consult us for free, which is free of charge.
However, can diabetes patients have bananas? The answer is that at the beginning of diabetes, people should limit the amount of bananas for it contains much sugar and the blood sugar level of diabetes patients is high. If we take in many bananas, it will increase blood sugar or glucose and worsen diabetes.
In addition, bananas also contain much potassium. If patients with diabetes develop into diabetic nephropathy, there may be high potassium in the blood especially in the advanced stage of diabetic nephropathy. In this case, if we take in more bananas, we will increase the disorder of electrolyte in the body.
So from the above, we can get a conclusion that we should pay attention to the intake of bananas. For more information, please surf on our website or consult us for free, which is free of charge.
Diabetes and High Blood Pressure
Generally, diabetes has no relationship with high blood pressure. There is also no doubt that some patients with diabetes are accompanied by high blood pressure.
For patients with type 1 diabetes, only those who have much albumin in urine can have high blood pressure. The blood pressure is normal for those who have little albumin in urine.
For patients with type 2 diabetes, blood pressure is connected with the age, obesity, blood sugar, blood fat, and the level of insulin. Bad control of blood sugar is usually the most critical factors, which plays an important role in the change of renal function.
Most patients with diabetes and high blood pressure have no complications, however, with the disease developing, many kinds of complications will appear when they are in advanced stage such as protein in urine, edema or swelling, fatigue, and so on.
So for patients with diabetes and high blood pressure, they should pay attention to the following aspects:
1. Control the intake of heat and sugar. Balance the intake of them, reduce the intake of sat fat. In addition, for those who have had diabetic nephropathy, reduce the intake of protein to some extent and limit the intake of salt.
2. Loose weight, which is considered to be the effective method which can control the blood sugar and blood pressure.
3. Taking exercise. Regular exercise can help loose weight and decrease the level of sugar in the blood. It is generally believed that blood pressure should be controlled at less than 140/90.
However, if the diabetes develops into diabetic nephropathy, we should take therapeutic measures such as stem cell therapy or Chinese medicine. For more information, please consult us online or email us.
For patients with type 1 diabetes, only those who have much albumin in urine can have high blood pressure. The blood pressure is normal for those who have little albumin in urine.
For patients with type 2 diabetes, blood pressure is connected with the age, obesity, blood sugar, blood fat, and the level of insulin. Bad control of blood sugar is usually the most critical factors, which plays an important role in the change of renal function.
Most patients with diabetes and high blood pressure have no complications, however, with the disease developing, many kinds of complications will appear when they are in advanced stage such as protein in urine, edema or swelling, fatigue, and so on.
So for patients with diabetes and high blood pressure, they should pay attention to the following aspects:
1. Control the intake of heat and sugar. Balance the intake of them, reduce the intake of sat fat. In addition, for those who have had diabetic nephropathy, reduce the intake of protein to some extent and limit the intake of salt.
2. Loose weight, which is considered to be the effective method which can control the blood sugar and blood pressure.
3. Taking exercise. Regular exercise can help loose weight and decrease the level of sugar in the blood. It is generally believed that blood pressure should be controlled at less than 140/90.
However, if the diabetes develops into diabetic nephropathy, we should take therapeutic measures such as stem cell therapy or Chinese medicine. For more information, please consult us online or email us.
Hypoglycemia in Diabetics
As we know, high blood glucose is the typical symptom of diabetes. So if patients with diabetes have low blood glucose, it is dangerous, which even threatens patients’ life. In this article, we will mainly introduce the symptoms when diabetes patients have low blood glucose and the instructions about how to prevent low blood glucose.
Generally, when patients with diabetes have shiver, nervosity, sweating, on edge, anxiety, worry, dizziness, hunger, lack of cooperation, sorrow, and so on, they will probably have low blood glucose.
How to prevent low blood glucose?
Firstly, before sexual behavior, patients had better test blood glucose. If the blood glucose level is less than 60 mg/dL, they should firstly solve this problem. Take in 10 to 15g sugar or other snacks which contain sugar. Patients had better put some sugar near the bed.
Secondly, diabetic patients who keep exercise will find out that low blood glucose may easily take place after a large amount of exercise. Normally, a large amount of exercise in the day will easily lead to low blood glucose in the evening or next day. So diabetic patients are suggested to test blood glucose now and then.
In addition, they can also adjust the injection intake of insulin. They can also have meal before going to bed if necessary, which can prevent low blood glucose effectively.
Of course, after diagnosed with diabetes, patients should treat as soon as possible.
Generally, when patients with diabetes have shiver, nervosity, sweating, on edge, anxiety, worry, dizziness, hunger, lack of cooperation, sorrow, and so on, they will probably have low blood glucose.
How to prevent low blood glucose?
Firstly, before sexual behavior, patients had better test blood glucose. If the blood glucose level is less than 60 mg/dL, they should firstly solve this problem. Take in 10 to 15g sugar or other snacks which contain sugar. Patients had better put some sugar near the bed.
Secondly, diabetic patients who keep exercise will find out that low blood glucose may easily take place after a large amount of exercise. Normally, a large amount of exercise in the day will easily lead to low blood glucose in the evening or next day. So diabetic patients are suggested to test blood glucose now and then.
In addition, they can also adjust the injection intake of insulin. They can also have meal before going to bed if necessary, which can prevent low blood glucose effectively.
Of course, after diagnosed with diabetes, patients should treat as soon as possible.
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