Thursday, May 23, 2013

Why Lupus Nephritis Patients Have Poor Urine Output

Lupus Nephritis can also be called SLE, a kind of kidney damage or kidney disorder which is caused by the spread of lupus in the body. In normal condition, people have 2000 to 2500 ml urine in 24 hours. However, for patients with Lupus Nephropathy, they can have less than 400 ml urine with 24 hours in the advanced stage of SLE, which is called poor urine.
Why does poor urine take place on patients with Lupus Nephritis? As we know, kidney has an important function: filtration. It can filtrate blood, thus causing urine every day after the reabsorption of renal tubules. After kidney is damaged, the filtration function will also be damaged accordingly, thus causing poor urine output, which usually takes place at the advanced stage of Lupus Nephropathy.
Can poor urine output be improved? Of course. Please do not worry. As long as there is urine, we can take measure to increase the renal glomerular filtration rate.
What should Lupus Nephropathy patients with poor urine do if they want to treat in our Hospital? Firstly, patients should have a systematic examination such as blood test, urine test, ECT and so on, which can show some index such as serum creatinine, GFR, etc, which can give us a general conclusion. In addition, they should also have an immune diagnosis so as to let doctors know how much the damage is, etc. Secondly, after immune diagnosis, patients with poor urine come into immune clearance stage, blood purification especially plasma exchange is applied, which can help clear away the immune complex and create a cleaner environment for the next steps. Next, patients will receive immune adjustment and immune protection, in which, Chinese Medicine and stem cells are applied, which can not only repair the damaged intrinsic cells but also increase the immunity, thus increasing GFR and dissolving poor urine output fundamentally.

Poor Urine output and Lupus Nephritis

Poor urine output makes Lupus Nephritis patients anxious. Do not worry. As long as we figure out the reason, we can take measures to treat it.
1. With the development of Lupus Nephritis, renal function is damaged, which makes the urine amount reduce, the diseases of which are such as acute renal glomerular nephritis, renal tumor, renal failure. If poor urine is caused by the above reasons, it indicates that the condition is serious.
2. When the blood which flows into kidney reduces, or when Lupus Nephritis patients have bleeding due to wound, shock, heart failure, and so on, patients can also suffer from renal failure, and have poor urine.
3. If Lupus Nephritis patients suffer from block of urinary tract, and patients don’t solve it in time, with time passing by, there will be water in renal pelvis, thus causing poor urine output.
Patients with Lupus Nephritis with poor urine should have a test about the serum creatinine, which is a relatively scientific index which can show how renal function is damaged. In addition, if it is convenient, patients can also have an ECT test, which is even more scientific diagnosis for patients with renal disease.
If it is caused by renal failure, we should treat it as kidney disease. In our hospital, we have immunotherapy for Lupus Nephritis is an auto-immune disease. In renal failure stage, patients have red blood cells, white blood cells and protein in urine, high blood pressure, rash and so on.
The immunotherapy can be divided into 6 steps: immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection.
Immune diagnosis can help us find out where the immune complex, the amount of immune complex, which can also supply an evidence for the treatment plan for the doctors in clinic.
Immune clearance is applied, such as blood dialysis, blood filtration, blood perfusion and plasma exchange, etc. For patients with Lupus Nephritis, they should choose plasma exchange in particular for plasma exchange can change the blood, thus clearing away the immune complex.
Immune adjustment and immune protection is operated by the application of Chinese Medicine and stem cells, etc, which can improve the blood circulation, dissolve the stasis, clear away the immune complex and increase the immunity.
After these, renal function can revive and poor urine can relieve.

Why SLE Has Ankle Edema

Why do patients with SLE have ankle edema? Edema in ankle is really a common and typical symptom in patients with SLE. In addition, patients can still have edema in face or eyelids. Generally, renal edema can be caused by two factors.
On one hand, the renal glomerular filtrate rate decreases, but the absorption of water and sodium in renal tubules is normal, which leads to the retention of water and sodium, thus causing the increased permeability of the capillaries in the whole body. In this case, water retention appears in the tissue space. The above condition is usually seen in glomerular nephritis.
On the other hand, with the development of SLE, a large amount of proteinuria appears, in which protein is lost, which leads to low protein in plasma. The osmotic pressure in plasma declines, so liquid flows and edema comes into being. In this case, ankle edema will also appear accordingly.

Monday, May 20, 2013

Lupus Nephritis Prognosis

Patients who are diagnosed with Lupus Nephritis will be concerned about the prognosis, wondering how it develops. Generally speaking, several years ago, most patients with Lupus Nephritis could not get a good prognosis if not treated well and about 20% of them would develop into renal failure after 10 years due to the activity of lupus, which makes people desperate.
However, with the medical technology developing, some scholars point out that about 50% of patients with Lupus Nephritis die of the disease. To our surprise, the other 50% patients die from the untoward effects which are caused by treatment such as hormone. Especially in recent years, Lupus Nephritis can be diagnosed earlier, so treatment schedule can be made accordingly, which makes patients with Lupus Nephritis have a better prognosis. So patients with Lupus Nephritis should be confident.
In addition, experts in this field also point out that infection is also an important factor which leads to the death of patients. So preventing infection is also a critical factor which doctors should pay more attention to. Infection prevention has become an important means to control the condition.
From the above, we can get a conclusion that three factors lead to the prognosis, which are activity of lupus, hormone and infection. What measures shall we take? To treat it, we should not use hormone any more and we should choose another one, which we will mainly explain in detail in this passage.
Lupus Nephritis is an autoimmune disease, so we mainly use immunotherapy, which can be divided into six steps: immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection. In these steps, Chinese Medicine is applied, which avoid the side effects which hormones lead in western countries. After these steps, not only immune complex is cleared but also immunity increases, thus stopping the recurrence of Lupus Nephritis.

End stage Renal Disease due to Lupus Nephritis

Lupus nephritis is an inflammation of the kidney caused by systemic lupus erythematosus (SLE), a disease of the immune system. Apart from the kidneys, SLE can also damage the skin, joints, nervous system and virtually any organ or system in the body.
With time passing by, if patients can not receive effective treatment, it will develop into end stage of renal disease, which can also be called uremia. In this stage, there are not only healthy and damaged intrinsic cells but also necrotic cells in the kidney. On the basis of its pathological mechanism, we researched out immunotherapy, which can be divided into 6 steps: immune diagnosis, immune clearance, immune inhibition, immune tolerance, immune adjustment and immune protection.
1. immune diagnosis
After a systematic diagnosis, we can figure out where the immune complex deposits exactly, the amount of immune complex and the exact type of immune response so that doctors can get more scientific diagnosis and arrange better treatment.
2. immune clearance
In immune clearance step, patients with SLE should clear away the immune complex in the blood, which can supply a cleaner inner environment for the treatment of kidney disease. For patients with SLE, the most proper blood purification method is the plasma exchange. Pay attention that the immune complex we clean is the one in the blood not the one on the kidney.
3. immune inhibition
The third one is immune inhibition. There is immune complex which deposit onto kidney, which leads to immune response. Medicine is used, which can stop the excessive immune response, thus stopping the inflammation response at a rapid speed.
4. immune tolerance
After immune inhibition, the immune response can be stopped. And the damage to the kidney can be blocked. However, the immune complex still deposit onto the kidney, which leads to a new series of immune response.
5. immune adjustment
In this step, Chinese medicines are applied, which can improve the blood circulation, including micro-blood circulation and dissolve the blood stasis. In this case, the immune complex can be discharged out, and the immune system can be repaired. Note that in this step, the immune complex we clean is the one on the kidney not the one in the blood. Blood purification such as dialysis and plasma exchange can not achieve this.
6. immune protection
In this stage, we use medicine which can nourish Qi and blood to rebuild the intrinsic immune system. In addition, biochemical cell therapy is also used in clinic such as the transplant of stem cell, which can also help achieve this effect.
After these steps, end stage of renal disease caused by lupus nephritis can relieve and the symptoms will disappear gradually.

Nephrotic Syndrome Secondary to SLE

What shall we do to treat Nephrotic Syndrome which is Secondary to SLE (Systemic Lupus Erythematosus)? Firstly, let’s know something about Systemic Lupus Erythematosus, which is the primary disease and causes Nephrotic Syndrome. people who are suffering from Nephrotic Syndrome Secondary to SLE must be told that it is an immune disease. What is immune disease? Generally speaking, immune disease means that it is the immune system out of order that causes the disease. In normal condition, our immune system is normal, which protects us and prevents us from getting caught by the disease. In order to figure out the solution of Nephrotic Syndrome Secondary to SLE, we should know about the reason why people are caught by kidney disease and there is no doubt that Nephrotic Syndrome is a kind of renal glomerular disease, which is a big group of kidney disease.
Now let’s come back to the question again: why people suffer from kidney disease.
Patients who have been suffering from kidney disease must know about a term immune complex, which is the combination of antigen and antibody. The deposition of the immune complex on the kidney cells or kidney tissues leads to the immune response or inflammatory reaction. If the immune system is abnormal, either intrinsic immune system or spare immune system is abnormal, the immune response or inflammatory reaction will never stop. In this case, on one hand, the immune complex can not be cleared away, on the other hand, the intrinsic cells and tissues in the kidney will be damaged. So it is generally believed that the key point of kidney disease treatment is to clear away the immune complex, which leads to the immune response even too allergic immune response.
However, in the whole world, experts in kidney disease research field have not found out an effective treatment method which can clear away the immune complex thoroughly. So we have to try to stop the immune reaction. To our disappointment, in most of time, immune reaction can not stopped either. Even sometimes, the immune reaction is controlled, there is still immune complex which deposit on the kidney, leading to a new circle of immune complex. At last, people may even develop into renal failure stage.
So how should we treat immune disease on earth? In our Hospital, we have created a new method which is both based on the western technology and traditional Chinese medicine. It can be divided into 6 steps: scientific diagnosis, scientific medicine, immune tolerance, immune adjustment and immune protection and immune clearance.
From the above, we can have known about the mechanism of kidney disease. And accordingly, we can also understand the reason why Nephrotic Syndrome Secondary to SLE takes place. For more information about the six-step therapy, please consult us online.

Why do People Get Lupus Nephritis

Definition
Lupus Nephritis is a kind of kidney damage which is caused by Systematic Lupus Nephritis. Systematic Lupus Nephritis (SLE) is also a kind of immune disease. In addition, from cytology, Systematic Lupus Nephritis is a kind of renal epithelial cell disease of capillary vessels. At present, doctors judge the disease by this.
Pathological factors
After patients are infected by lupus, excessive immune response will come into being and exist, which leads to the pathological self-antibody. In this case, a large amount of immune complex comes into being. C3、lgG、lgM and so on will deposit on renal capillary epithelial cells. At this time, the immune mediator in renal capillary epithelial cells will come into being, so the normal function of renal capillary epithelial cells will be damaged as well. There are negative charges barrier in the epithelial cells. After the function is damaged, protein will pass and flow into urine, thus causing proteinuria. From the urine report, we can find out that there are pluses. Renal function will be damaged accordingly.
Treatment principle
To treat Systematic Lupus Nephritis (SLE), we should follow the following procedures.
Firstly, extending blood vessels, the purpose of which is to improve the blood circulation in the kidney, relieve the insufficiency of blood and oxygen in the blood, thus creating a favorable environment for the repair of epithelial cells and mesangial cells.
Secondly, anti-inflammation, the purpose of which is to reduce the infiltration of inflammatory cells and relieve the further damage of renal epithelial cells.
Thirdly, anticoagulation, the purpose of which is to relieve of pressure which forms thrombus and lay a foundation for the repair of epithelial cells.
Fourthly, degradation, which is used to clear the immune complex and matrix and helps them discharge out of the body.
Medicines
As for the medicine, patients with Systematic Lupus Nephritis (SLE) are recommended to take combination of western medicine and Chinese medicine, which can achieve better effect than only either of them for either western medicine or Chinese medicine has restriction. In our hospital, we have created six-step immune therapy on the basis of this theory, which can repair the damaged intrinsic cells as well as increase the immune ability.